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2 OMIM references -
1 associated gene
14 signs/symptoms
PROTEIN INTERACTIONS: 1
4 OMIM references -
5 associated genes
No signs/symptoms info
Hereditary thrombophilia due to congenital protein S deficiency
Herpetic encephalitis

PROS1 TBK1
TICAM1
TLR3
TRAF3
UNC93B1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
PROS1
(0.63)
TBK1



Citations in the biomedical literature:


Hereditary thrombophilia due to congenital protein S deficiency
PROS1
Herpetic encephalitis
TBK1 TICAM1 TLR3 TRAF3 UNC93B1



Hereditary thrombophilia due to congenital protein S deficiency
Herpetic encephalitis

Synonym(s):
(no synonyms)

Synonym(s):
- HSV encephalitis
- Herpes simplex encephalitis
- Herpes simplex neuroinvasion

Classification (Orphanet):
(no data available)
Classification (Orphanet):
- Rare genetic disease
- Rare immune disease
- Rare infectious disease
- Rare neurologic disease

Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Classification (ICD10):
(no data available)

Epidemiological data:
Class of prevalence: 1-9 / 1 000 000
Average age onset: neonatal/infancy
Average age of death: -
Type of inheritance: autosomal recessive
Epidemiological data:
Class of prevalence: unknown
Average age onset: variable
Average age of death: any age
Type of inheritance: sporadic

External references:
2 OMIM references -
No MeSH references
External references:
4 OMIM references -
No MeSH references

Hereditary thrombophilia due to congenital protein S deficiency

Very frequent
- Autosomal dominant inheritance
- Purpura / petichiae

Frequent
- Anomalies of skin, subcutaneous tissue and mucosae
- Retinopathy
- Skin hypoplasia / aplasia / atrophy
- Thin skin
- Venous thrombosis / phlebitis / thrombophlebitis

Occasional
- Abnormal pigmentary skin changes / skin pigmentation anomalies
- Arterial embolism / thrombosis
- Cerebral vascular anomalies
- Chronic skin infection / ulcerations / ulcers / cancrum
- Gangrena / necrosis
- Pulmonary thromboembolism
- Varices / varicous veins / venous insufficiency


Herpetic encephalitis

(no data available)